Diabetes and Lipid Clinic of Alaska



With ZETIA and a statin, you can fight cholesterol
on both fronts.

Cholesterol-lowering medicines, called statins, such as Zocor (simvastatin), Lipitor (atorvastatin), Pravachol (pravastatin), and Crestor (rosuvastatin), work mainly with your liver to decrease production of cholesterol and reduce cholesterol in your bloodstream. ZETIA works differently. Statins work mainly with the liver. ZETIA works in the digestive tract, as do some other medicines. But ZETIA is unique in the way it helps block the absorption of cholesterol that comes from food. So, it complements what you are already doing.

ZETIA lowers cholesterol when taken by itself, too.

A healthy diet and exercise are important, but sometimes they’re just not enough to get your cholesterol where it needs to be. ZETIA is proven to complement those efforts and, when added to a healthy diet, is proven to lower Bad (LDL-C) Cholesterol by as much as 30 points—about 18%. These are average results. Individual results may vary. You should continue to eat right and stay active, but if that's not enough, ask your doctor if ZETIA is right for you.

In clinical studies, ZETIA lowered LDL (Bad) Cholesterol in patients who weren't taking a cholesterol-lowering medicine and couldn't control their high cholesterol with diet and exercise alone. That means, even when taken by itself, ZETIA, along with diet, still can help lower your cholesterol.

Important information about ZETIA

ZETIA is a prescription medicine and should not be taken by people who are allergic to any of its ingredients. ZETIA can be taken alone or with a statin. Statins should not be taken by women who are nursing or pregnant or who may become pregnant, or by anyone with liver problems. If you have ever had liver problems or are pregnant or nursing, your doctor will decide if ZETIA alone is right for you. Your doctor may do blood tests to check your liver before you start taking ZETIA with a statin and during treatment.

Unexplained muscle pain or weakness could be a sign of a rare but serious side effect and should be reported to your doctor right away. Patients reported few side effects while taking ZETIA, including tiredness and stomach pain.